hexavalent chromium cancer

Triangle Park, NC: National Institute of Environmental Health and Safety, 2016. According to NIOSH, Hexavalent Chromium is well-established as a carcinogen associated with lung, nasal, and sinus cancer. Hexavalent chromium (Cr(VI)) compounds are a large group of chemicals with varying properties, uses, and workplace exposures. The National Institutes of Health reports unequivocally that Chromium hexavalent (VI) compounds are known to cause cancer in humans based on sufficient evidence of carcinogenicity from studies in humans. In addition, chromium caused mouth cancers, and infiltrated the cells of many organs, including livers and pancreatic lymph nodes. Cr(VI) is known to cause cancer. As an anticorrosive agent, it is also added to stainless steel, which releases hexavalent chromium during welding. Hexavalent chromium is likely key to all materials made from chromium. The mortality experience in a previously studied cohort of 2,357 chromate chemical production workers with 122 lung cancer deaths was analyzed with Poisson regression methods. Research Triangle Park, NC: U.S. Environmental Protection Agency, 2011. It was based on a 1968 study in Germany that found stomach tumors in animals that drank the substance. National Toxicology Program scientists reported that their two-year animal study “clearly demonstrates” that the compound is carcinogenic in drinking water. Hexavalent Chromium, Yellow Water, and Cancer A Convoluted Saga Allan H. Smith Abstract: In this issue, Beaumont et al report cancer mortality rates associated with exposure to high concentrations of hexavalent chro-mium in well water in Liaoning Province, China. Cancer Risk: Chromium VI Epidemiological studies of workers have clearly established that inhaled chromium is a human carcinogen, resulting in an increased risk of lung cancer. National Toxicology Program results "clearly" indicate that the heavy metal is carcinogenic. There also is human evidence that drinking hexavalent chromium-contaminated water can cause cancer. The national standard is 100 ppb. This map shows predicted levels of hexavalent chromium in outdoor air at residential locations in Canada in 2011. Hexavalent chromium compounds are used widely in metal finishing and chrome plating, stainless steel production, leather tanning, and wood preservatives. Hexavalent chromium compounds have been used as corrosion inhibitors in a wide variety of products and processes. Inhalation of hexavalent chromium is a known cause of lung cancer, 3 but, as noted by Beaumont et al, animal bioassays have reported that chromium ingestion also causes intestinal tract tumors. This carcinogenic form of chromium was at the heart of a lawsuit in California’s Central Valley by Erin Brockovich, which became the subject of … Watch Your Plastics, Toxic Coal Ash Hits Poor and Minority Communities Hardest. © 2020 Scientific American, a Division of Springer Nature America, Inc. Support our award-winning coverage of advances in science & technology. Welding on stainless steel can expose welders to hexavalent chromium, also called Chrome 6, or Chrome (VI), which is a suspect cancer-causing substance now specifically regulated by OSHA (General Industry 29 CFR 1910.1026 and Construction 29 CFR 1926.1126). Does Hexavalent Chromium Cause Cancer? Exposure to chromium 6 compounds can increase the risk of lung cancer. However, Gwiazda said, using the new research “to support a drinking water standard is a different matter” because extrapolating it to humans remains controversial. 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